Abiba Pharmacia Private Limited

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Tazocia-4.5 gm
Piperacillin 4000mg and Tazobactam 500mg Injection is a combination antibiotic formulation designed to treat severe bacterial infections. This combination includes Piperacillin, a broad-spectrum penicillin-class antibiotic, and Tazobactam, a beta-lactamase inhibitor that enhances the efficacy of Piperacillin by overcoming bacterial resistance.

Key Features:

1. Active Ingredients:

   • Piperacillin (4 gm): Effective against a wide range of gram-positive and gram-negative bacteria.
   • Tazobactam (0.5 gm): Protects Piperacillin from degradation by beta-lactamase enzymes, extending its spectrum of activity.

Indications:

This combination is used to treat serious infections caused by susceptible bacteria, including:

1. Respiratory Tract Infections: Severe pneumonia, hospital-acquired infections, and ventilator-associated pneumonia.
2. Urinary Tract Infections (UTIs): Complicated infections, including pyelonephritis.
3. Intra-Abdominal Infections: Peritonitis and abscesses.
4. Skin and Soft Tissue Infections: Cellulitis, diabetic foot infections, and infected wounds.
5. Sepsis and Bloodstream Infections: Severe systemic infections requiring broad-spectrum antibiotic coverage.

Benefits:

1. Broad-Spectrum Activity: Effective against a wide range of gram-positive, gram-negative, and anaerobic bacteria.
2. Enhanced Efficacy: Tazobactam overcomes resistance caused by beta-lactamase-producing organisms.
3. Reliable Treatment: Proven efficacy for managing severe and complicated infections.
4. Hospital-Grade Use: Widely used in critical care settings to treat life-threatening infections.

Dosage & Administration:

• Typical Dosage:

  • Administered every 6 to 8 hours as an intravenous (IV) infusion over 30 minutes or as directed by a healthcare professional.
  • Dosage depends on the infection type, severity, and patient’s renal function.

• Method of Administration:

  • Reconstitute the injection with an appropriate diluent, such as sterile water or saline, as per the product guidelines.
  • Ensure aseptic techniques during preparation and administration.

Important: Always follow the dosage and schedule prescribed by a qualified healthcare provider.

Safety Information:

• Common Side Effects:
  • Nausea, diarrhea, rash, injection site reactions, or elevated liver enzymes.
• Precautions:
  • Use with caution in patients with a history of allergies to penicillins, cephalosporins, or beta-lactam antibiotics.
  • Monitor kidney function regularly, especially in patients with renal impairment.
  • Avoid use during pregnancy or breastfeeding unless deemed necessary by a healthcare provider.
• Contraindications:
  • Known hypersensitivity to Piperacillin, Tazobactam, or any beta-lactam antibiotics.

Storage:

• Store the vial in a cool, dry place, away from direct sunlight.
• Use the reconstituted solution immediately or store as per the product guidelines to prevent contamination.
• Keep out of reach of children.

Note: This medication is for use under the supervision of qualified healthcare professionals in hospital settings. Misuse or overuse of antibiotics can lead to the development of resistance, reducing their efficacy. Ensure close monitoring of the patient’s condition and laboratory parameters during therapy.

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